Modern approaches to pharmacotherapy of tuberculosis infection in children

نویسندگان

چکیده

Anti-TB drugs for children: Aetiotropic therapy is used the treatment of tuberculosis (TB) in children, as well adult patients. Anti-tuberculosis (anti-TB drugs) are divided into 3 lines, taking account drug sensitivity Mycobacterium (MBT). First-line anti-TBdrugs (basic) to treat TB caused by drug-susceptible MBT. Second- and third-line (reserve) recommended MBT-induced multidrug-resistant (MDR) extensively drug-resistant (XDR) TB, respectively.
 Stages regimens tuberculosis: Chemotherapy children carried out 2 stages (intensive continuation treatment) includes 5 regimens. Each regimen assumes a certain combination anti-TB drugs, indicating duration frequency their administration. The final chemotherapy chosen only according results determining sensitivity. To improve epidemic among it important use drugs. effectiveness anti-tuberculosis pharmacotherapy largely determined MBT rational choice regimen. wrong or its violation threatens reduce expand spectrum resistance pathogen. development fixed-dose special dosage forms will quality adherence treatment. Pharmacoeconomic studies needed increase infection optimize costs implementation.

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ژورنال

عنوان ژورنال: Research results in pharmacology

سال: 2021

ISSN: ['2658-381X']

DOI: https://doi.org/10.3897/rrpharmacology.7.66627